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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1B
All Species:
16.97
Human Site:
S1620
Identified Species:
28.72
UniProt:
Q9UPS6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPS6
NP_055863.1
1923
208732
S1620
P
A
G
S
P
E
L
S
P
P
Q
P
L
F
R
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
P1409
R
P
P
P
P
P
P
P
P
P
P
R
A
Y
E
Rhesus Macaque
Macaca mulatta
XP_001092031
624
66545
V340
N
S
P
A
V
T
A
V
A
G
A
T
A
A
F
Dog
Lupus familis
XP_543382
1925
209302
S1622
A
P
A
S
P
E
L
S
P
P
Q
P
L
F
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
S1682
P
S
A
S
P
E
P
S
P
P
Q
P
L
F
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510235
695
75024
D411
T
L
F
A
P
H
A
D
D
S
P
A
F
G
S
Chicken
Gallus gallus
Q5F3P8
2008
223067
S1705
V
I
P
S
P
E
Y
S
P
P
Q
P
Q
F
R
Frog
Xenopus laevis
Q66J90
1938
216239
S1635
T
L
P
S
P
E
Y
S
P
P
R
A
M
F
K
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
S1540
S
M
H
S
P
V
A
S
P
R
R
P
S
F
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
I1356
K
G
I
D
A
E
D
I
N
F
I
K
M
S
Y
Honey Bee
Apis mellifera
XP_395451
1406
159180
L1122
D
A
E
D
V
E
Y
L
R
R
S
Y
E
A
L
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
L1223
D
L
E
D
Q
W
Y
L
R
A
A
L
N
E
M
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
T1625
P
L
A
I
V
D
H
T
Y
C
Q
K
P
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
L1029
R
K
F
G
T
A
K
L
D
C
D
A
E
L
W
Conservation
Percent
Protein Identity:
100
37.3
27.9
91.9
N.A.
87.7
N.A.
N.A.
23.1
61.5
55
51
N.A.
24.7
23.9
22.3
21.3
Protein Similarity:
100
50.3
28.8
93.9
N.A.
90.2
N.A.
N.A.
26.7
71.1
66.6
63.6
N.A.
39.4
38.6
35.2
35.2
P-Site Identity:
100
20
0
80
N.A.
80
N.A.
N.A.
6.6
66.6
46.6
40
N.A.
6.6
13.3
0
13.3
P-Site Similarity:
100
26.6
13.3
80
N.A.
86.6
N.A.
N.A.
13.3
66.6
66.6
46.6
N.A.
13.3
13.3
0
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
22
15
8
8
22
0
8
8
15
22
15
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% C
% Asp:
15
0
0
22
0
8
8
8
15
0
8
0
0
0
0
% D
% Glu:
0
0
15
0
0
50
0
0
0
0
0
0
15
8
8
% E
% Phe:
0
0
15
0
0
0
0
0
0
8
0
0
8
43
8
% F
% Gly:
0
8
8
8
0
0
0
0
0
8
0
0
0
8
0
% G
% His:
0
0
8
0
0
8
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
8
0
0
0
8
0
0
8
0
0
0
0
% I
% Lys:
8
8
0
0
0
0
8
0
0
0
0
15
0
0
8
% K
% Leu:
0
29
0
0
0
0
15
22
0
0
0
8
22
8
8
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
15
0
15
% M
% Asn:
8
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% N
% Pro:
22
15
29
8
58
8
15
8
50
43
15
36
8
0
8
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
36
0
8
0
0
% Q
% Arg:
15
0
0
0
0
0
0
0
15
15
15
8
0
0
29
% R
% Ser:
8
15
0
43
0
0
0
43
0
8
8
0
8
8
8
% S
% Thr:
15
0
0
0
8
8
0
8
0
0
0
8
0
8
0
% T
% Val:
8
0
0
0
22
8
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
29
0
8
0
0
8
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _